Analysis Tools
hematopoietic system
|
• CD25-positive CD4 T cells were almost completely absent in the lymph nodes and spleen, indicating that IL2 is needed to maintain this regulatory T subset
|
|
• in the thymus, there is a substantial increase in the frequency and absolute numbers of CD25-positive CD4 T cells that have the characteristics of regulatory T cells
• this phenotype is similar to mice that express the same transgenes but have the Il2 locus intact, indicating that IL2 is not needed to generate this regulatory T cell subset
|
|
• in the thymus, CD25-positive CD4 T cells express high levels of Foxp3
• this phenotype in the thymus is similar to transgenic mice that have the Il2 locus intact, indicating that IL2 is not needed to generate this regulatory T cell subset
• only 0.5% of CD25-positive CD4 T cells in the lymph nodes and spleen express Foxp3 compared to 9% of these cells in transgenic mice with the Il2 locus intact
|
immune system
|
• CD25-positive CD4 T cells were almost completely absent in the lymph nodes and spleen, indicating that IL2 is needed to maintain this regulatory T subset
|
|
• in the thymus, there is a substantial increase in the frequency and absolute numbers of CD25-positive CD4 T cells that have the characteristics of regulatory T cells
• this phenotype is similar to mice that express the same transgenes but have the Il2 locus intact, indicating that IL2 is not needed to generate this regulatory T cell subset
|
|
• in the thymus, CD25-positive CD4 T cells express high levels of Foxp3
• this phenotype in the thymus is similar to transgenic mice that have the Il2 locus intact, indicating that IL2 is not needed to generate this regulatory T cell subset
• only 0.5% of CD25-positive CD4 T cells in the lymph nodes and spleen express Foxp3 compared to 9% of these cells in transgenic mice with the Il2 locus intact
|
