Phenotypes Associated with This Genotype

Genotype
MGI:3768653

• Allelic Composition: Cdkn2a^tm1Rdp/Cdkn2a⁺; Tg(Tyr-NRAS*Q61K)1Bee/?
• Genetic Background: involves: 129/Sv * C57BL/6 * DBA/2 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased cutaneous melanoma incidence ( J:98545 )

• 15 of 18 mice develop cutaneous melanomas within 12 months of birth

integument

increased cutaneous melanoma incidence ( J:98545 )

• 15 of 18 mice develop cutaneous melanomas within 12 months of birth

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
skin melanoma		DOID:8923	OMIM:608035 OMIM:612263	J:98545