Phenotypes for Ahsp Hbb-b1 Hbb-b2 MGI:3769340 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ahsp^tm1Mjwe/Ahsp⁺ Hbb-b1^tm1Unc/Hbb-b1⁺ Hbb-b2^tm1Unc/Hbb-b2⁺
Genetic Background	involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ahsp^tm1Mjwe mutation (0 available); any Ahsp mutation (1 available)
Hbb-b1^tm1Unc mutation (2 available); any Hbb-b1 mutation (7 available)
Hbb-b2^tm1Unc mutation (2 available); any Hbb-b2 mutation (5 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

anemia ( J:94421 )

• embryos are anemic

decreased hematocrit ( J:94421 )

• decreased to 27.5% from ~55% in wild-type embryos

integument

pallor ( J:94421 )

• embryos are pale

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
beta thalassemia		DOID:12241	OMIM:613985	J:94421

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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