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Phenotypes Associated with This Genotype
Genotype
MGI:3769340
Allelic
Composition		 Ahsptm1Mjwe/Ahsp+
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ahsptm1Mjwe mutation (0 available); any Ahsp mutation (1 available)
Hbb-b1tm1Unc mutation (2 available); any Hbb-b1 mutation (7 available)
Hbb-b2tm1Unc mutation (2 available); any Hbb-b2 mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
anemia ( J:94421 )
• embryos are anemic
decreased hematocrit ( J:94421 )
• decreased to 27.5% from ~55% in wild-type embryos

integument
pallor ( J:94421 )
• embryos are pale

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
beta thalassemia DOID:12241 OMIM:613985
 J:94421

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory