Phenotypes Associated with This Genotype

Genotype
MGI:3769780

• Allelic Composition: Del(7Herc2-Mkrn3)13FRdni/+
• Genetic Background: involves: C57BL/6 * CD-1 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality ( J:56614 )

• when this allele is inherited paternally, mice die within a week of birth

• however, when this allele is inherited maternally mice are normal

homeostasis/metabolism

dehydration ( J:56614 )

• when this allele is inherited paternally, mice exhibit dehydration despite milk in their stomachs

behavior/neurological

decreased locomotor activity ( J:56614 )

• when this allele is inherited paternally, mice exhibit reduced movement compared to wild-type mice

respiratory system

abnormal respiration ( J:56614 )

• when this allele is inherited paternally, mice exhibit irregular breathing

cellular

maternal imprinting ( J:56614 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Prader-Willi syndrome		DOID:11983	OMIM:176270	J:56614