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Phenotypes Associated with This Genotype
Genotype
MGI:3770665
cx16
Allelic
Composition		 Als2tm1Deng/Als2tm1Deng
Tg(SOD1*G93A)1Gur/?
Genetic
Background		 involves: 129/Sv * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Als2tm1Deng mutation (0 available); any Als2 mutation (88 available)
Tg(SOD1*G93A)1Gur mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:129939 )
• all mice die of a neurodegenerative disorder by 150 days of age

nervous system
neurodegeneration ( J:129939 )
• mice display neurodegeneration similar to mice with just the Tg(SOD1*G93A)1Gur transgene

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory