Phenotypes for Notch1 MGI:3775287 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Notch1^tm2Pst/Notch1^tm2.1Pst
Genetic Background	B6.Cg-Notch1^tm2.1Pst

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Notch1^tm2.1Pst mutation (0 available); any Notch1 mutation (118 available)
Notch1^tm2Pst mutation (0 available); any Notch1 mutation (118 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:131563 )

• mice die at E10

embryo

embryonic growth retardation ( J:131563 )

• at E9.5, mice exhibit 13 to 17 somites compared to 23 to 26 in Notch1^tm2Pst homozygotes

growth/size/body

embryonic growth retardation ( J:131563 )

• at E9.5, mice exhibit 13 to 17 somites compared to 23 to 26 in Notch1^tm2Pst homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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