Phenotypes for Igkrs Tg(BCL2)22Wehi MGI:3776233 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Igkrs^tm1Nemz/Igkrs^tm1Nemz Tg(BCL2)22Wehi/?
Genetic Background	involves: 129 * C57BL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igkrs^tm1Nemz mutation (1 available); any Igkrs mutation (1 available)
Tg(BCL2)22Wehi mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased anti-double stranded DNA antibody level ( J:132125 )

• there is a significant increase in IgG and IgM antibodies that bind DNA in the sera of 5 month old mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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