Phenotypes Associated with This Genotype

Genotype
MGI:3776525

hm2

• Allelic Composition: Ahr^tm1Gonz/Ahr^tm1Gonz
• Genetic Background: involves: 129S4/SvJae * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased susceptibility to xenobiotic induced morbidity/mortality ( J:113285 )

• unlike C57BL/6-Ahr^b-1 neonates, mice are not susceptible to lethality induced by in utero exposure to cHBB

reproductive system

decreased litter size ( J:113285 )

• mice produce smaller litters than wild-type mice

• however, exposure to cHBB does not further decrease fecundity

homeostasis/metabolism

decreased susceptibility to xenobiotic induced morbidity/mortality ( J:113285 )

• unlike C57BL/6-Ahr^b-1 neonates, mice are not susceptible to lethality induced by in utero exposure to cHBB

decreased physiological sensitivity to xenobiotic ( J:113285 )

• unlike C57BL/6-Ahr^b-1 neonates, mice are not susceptible to lethality induced by in utero exposure to cHBB