About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3783593
Allelic
Composition
Nlgn4lGt(XST093)Byg/Nlgn4lGt(XST093)Byg
Genetic
Background
B6.129P2-Nlgn4xGt(XST093)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nlgn4lGt(XST093)Byg mutation (1 available); any Nlgn4l mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• attack latencies and frequency to an unfamiliar intruder mouse in the resident were reduced
• mutant mice spent 45% less time in direct contact with each other than wild-type control in an open arena
• no social preference to investigate unfamiliar mouse
• the latency to start calling and frequency of calls by male mice upon contact with a female mouse in estrous were reduced

nervous system
• small but significant reductions in the volume of the total brain and brainstem

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
autism spectrum disorder DOID:0060041 J:131843


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory