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Phenotypes Associated with This Genotype
Genotype
MGI:3783593
Allelic
Composition
Nlgn4lGt(XST093)Byg/Nlgn4lGt(XST093)Byg
Genetic
Background
B6.129P2-Nlgn4xGt(XST093)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nlgn4lGt(XST093)Byg mutation (1 available); any Nlgn4l mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• attack latencies and frequency to an unfamiliar intruder mouse in the resident were reduced
• mutant mice spent 45% less time in direct contact with each other than wild-type control in an open arena
• no social preference to investigate unfamiliar mouse
• the latency to start calling and frequency of calls by male mice upon contact with a female mouse in estrous were reduced

nervous system
• small but significant reductions in the volume of the total brain and brainstem

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
autism spectrum disorder DOID:0060041 J:131843


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/09/2024
MGI 6.24
The Jackson Laboratory