behavior/neurological
• attack latencies and frequency to an unfamiliar intruder mouse in the resident were reduced
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• mutant mice spent 45% less time in direct contact with each other than wild-type control in an open arena
• no social preference to investigate unfamiliar mouse
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• the latency to start calling and frequency of calls by male mice upon contact with a female mouse in estrous were reduced
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nervous system
• small but significant reductions in the volume of the total brain and brainstem
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
autism spectrum disorder | DOID:0060041 | J:131843 |