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Phenotypes Associated with This Genotype
Genotype
MGI:3784582
Allelic
Composition		 Cryaatm1.1Ady/Cryaa+
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cryaatm1.1Ady mutation (0 available); any Cryaa mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Lens opacity in Cryaatm1.1Ady/Cryaa+, and Cryaatm1.1Ady/Cryaatm1.1Ady mice and microphthalmia in Cryaatm1.1Ady/Cryaatm1.1Ady mice

vision/eye
abnormal lens morphology ( J:132296 )
• increased amounts of alphaA-crystallin and alphaB-crystallin in the lens-insoluble fractions at lesser degree than homozygous mice
cataract ( J:132296 )
• less severe lens opacities in heterozygous mice compared to homozygotes

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
cataract 9 multiple types DOID:0110266 OMIM:604219
 J:132296

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory