Phenotypes for Lama2 MGI:3789335 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Lama2^dy-2J/Lama2^dy-2J
Genetic Background	B6.WK-Lama2^dy-2J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lama2^dy-2J mutation (1 available); any Lama2 mutation (177 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

enhanced long-term potentiation ( J:97464 )

• unlike in wild-type mice, one third of Purkinje cells observed exhibit long term potentitation when evoked excitatory postsynaptic potentials are recorded

reduced long-term depression ( J:97464 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
congenital merosin-deficient muscular dystrophy 1A		DOID:0110636	OMIM:607855	J:97464

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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