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Phenotypes Associated with This Genotype
Genotype
MGI:3793284
hm1
Allelic
Composition		 Ror2tm1Ymi/Ror2tm1Ymi
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ror2tm1Ymi mutation (0 available); any Ror2 mutation (126 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
brachyphalangia ( J:134490 )
• short but all phalanges are present unlike in mice homozygous for Ror2tm1Anec

skeleton
brachyphalangia ( J:134490 )
• short but all phalanges are present unlike in mice homozygous for Ror2tm1Anec

hearing/vestibular/ear
abnormal organ of Corti morphology ( J:140886 )
• organization is disrupted at E18.5
abnormal cochlear hair cell morphology ( J:140886 )
• some show randomized orientation of auditory hair cells
abnormal cochlear outer hair cell morphology ( J:140886 )
• alignment of outer hair cells into three rows is disturbed

nervous system
abnormal cochlear hair cell morphology ( J:140886 )
• some show randomized orientation of auditory hair cells
abnormal cochlear outer hair cell morphology ( J:140886 )
• alignment of outer hair cells into three rows is disturbed

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory