Phenotypes for Scrib Vangl2 MGI:3797053 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Scrib^Crc/Scrib⁺ Vangl2⁺/Vangl2^Lp
Genetic Background	involves: BALB/c * C57BL/6 * CBA/Ca * LPT/LeJ * NMRI * SWR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scrib^Crc mutation (3 available); any Scrib mutation (53 available)
Vangl2^Lp mutation (2 available); any Vangl2 mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

spina bifida ( J:72608 )

craniorachischisis ( J:72608 )

• 29 of 54 double heterozygotes exhibit craniorachisichisis and the remainder had either spina bifida or a looped tail

limbs/digits/tail

curly tail ( J:72608 )

• in a small minority of double heterozygotes

embryo

spina bifida ( J:72608 )

craniorachischisis ( J:72608 )

• 29 of 54 double heterozygotes exhibit craniorachisichisis and the remainder had either spina bifida or a looped tail

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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