Analysis Tools
mortality/aging
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• mice die between 6 and 17 days after birth
• however, prenatal lethality observed in Relatm1Bal homozygotes is reversed
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hematopoietic system
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• at the time of death mice exhibit foci of degeneration in the thymus
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• in the liver of 2 to 7 day old mice
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• at the time of death, mice exhibit less compact germinal centers compared to in wild-type mice
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• at the time of death
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liver/biliary system
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• at the time of death mice, exhibit acute hepatitis with massive neutrophilic infiltration and necrotic foci
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• at the time of death
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cardiovascular system
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• at the time of death, some mice exhibit neutrophilic infiltration of the heart and lungs
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growth/size/body
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• within the first week after birth, mice become runted despite continued nursing
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respiratory system
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• at the time of death, some mice exhibit neutrophilic infiltration of the heart and lungs
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immune system
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• at the time of death, some mice exhibit neutrophilic infiltration of the heart and lungs
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• at the time of death mice exhibit foci of degeneration in the thymus
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• at the time of death, mice exhibit less compact germinal centers compared to in wild-type mice
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• at the time of death
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• at the time of death mice, exhibit acute hepatitis with massive neutrophilic infiltration and necrotic foci
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• at the time of death, some mice exhibit neutrophilic infiltration of the heart and lungs
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endocrine/exocrine glands
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• at the time of death mice exhibit foci of degeneration in the thymus
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