Phenotypes for Fas Raf1 MGI:3799535 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Fas^lpr/Fas^lpr Raf1^tm1Bacc/Raf1^tm1Bacc
Genetic Background	involves: 129/SvHsd * 129P2/OlaHsd * C57BL/6 * MRL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fas^lpr mutation (39 available); any Fas mutation (83 available)
Raf1^tm1Bacc mutation (0 available); any Raf1 mutation (116 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

abnormal erythropoiesis ( J:135681 )

• differentiation of erythroblasts is blocked even at 60 hours after induction of differentiation, as measured by cell proliferation, volume decrease, and hemoglobin accumulation

cellular

increased apoptosis ( J:135681 )

• number of apoptotic erthroblasts is increased under 10U/ml of erythropoietin

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24