Phenotypes Associated with This Genotype

Genotype
MGI:3804218

cn7

• Allelic Composition: Rb1^tm2Brn/Rb1^tm2Brn; Tg(Gfap-cre)2Brn/0
• Genetic Background: involves: 129 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:187257 )

neoplasm

neoplasm ( J:61961 )

N • mutants do not develop medulloblastomas

increased pituitary gland tumor incidence ( J:187257 )

increased carcinoma incidence ( J:187257 )

• large cell carcinoma

endocrine/exocrine glands

increased pituitary gland tumor incidence ( J:187257 )

nervous system

increased pituitary gland tumor incidence ( J:187257 )