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Phenotypes Associated with This Genotype
Genotype
MGI:3804632
cn1
Allelic
Composition
Eomestm1Srnr/Eomestm1Srnr
Tg(Cd4-cre)1Cwi/0
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eomestm1Srnr mutation (1 available); any Eomes mutation (44 available)
Tg(Cd4-cre)1Cwi mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• unlike mice with T-cell specific conditional deletion of Eomes that also lack expression of Tbx21, clearance of lymphocyte choriomeningitis virus is similar to wild-type controls
• deficiency in memory-phenotype CD8+ T cells

hematopoietic system
• deficiency in memory-phenotype CD8+ T cells


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory