Phenotypes Associated with This Genotype

Genotype
MGI:3806464

• Allelic Composition: Robo1^tm1Phr/Robo1⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased lymphoma incidence ( J:93666 )

• spontaneously develop lung lymphomas and carcinomas during the second year of life with a 3-fold increase in incidence compared with controls

increased carcinoma incidence ( J:93666 )

• spontaneously develop lung lymphomas and carcinomas during the second year of life with a 3-fold increase in incidence compared with controls

increased lung adenocarcinoma incidence ( J:93666 )

• 26.5% of tumors that develop in heterozygotes are lung adenocarcinomas

respiratory system

increased lung adenocarcinoma incidence ( J:93666 )

• 26.5% of tumors that develop in heterozygotes are lung adenocarcinomas

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
lung cancer		DOID:1324	OMIM:211980 OMIM:608935 OMIM:612571 OMIM:612593 OMIM:614210	J:93666