Phenotypes Associated with This Genotype

Genotype
MGI:3810335

hm1

• Allelic Composition: Myo15a^sh2/Myo15a^sh2
• Genetic Background: Mixed stock

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hearing/vestibular/ear

abnormal cochlear outer hair cell morphology ( J:158897 )

• most outer hair cells exhibit a non-convex region on their apical circumference unlike wild-type cells

• outer hair cells exhibit a slight flattening of their neural side compared to in wild-type mice

short outer hair cell stereocilia ( J:132633 , J:158897 )

• hair cell stereocilia are shorter than in wild-type mice (J:132633)

nervous system

abnormal cochlear outer hair cell morphology ( J:158897 )

• most outer hair cells exhibit a non-convex region on their apical circumference unlike wild-type cells

• outer hair cells exhibit a slight flattening of their neural side compared to in wild-type mice

short outer hair cell stereocilia ( J:132633 , J:158897 )

• hair cell stereocilia are shorter than in wild-type mice (J:132633)