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Phenotypes Associated with This Genotype
Genotype
MGI:3810651
cn5
Allelic
Composition		 Gt(ROSA)26Sortm1Fia/Gt(ROSA)26Sor+
Nf1tm1Par/Nf1tm1Par
Tg(Fabp7-cre,-lacZ)3Gtm/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1Fia mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Nf1tm1Par mutation (4 available); any Nf1 mutation (161 available)
Tg(Fabp7-cre,-lacZ)3Gtm mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
small adenohypophysis ( J:138868 )
• significantly smaller than control littermates

growth/size/body
decreased body weight ( J:138868 )

endocrine/exocrine glands
small adenohypophysis ( J:138868 )
• significantly smaller than control littermates

homeostasis/metabolism
decreased circulating growth hormone level ( J:138868 )
• reduction in liver Igf1 mRNA levels indicates a reduction in circulating growth hormone levels

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory