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Phenotypes Associated with This Genotype
Genotype
MGI:3817641
cn1
Allelic
Composition
Gata3tm1Jfz/Gata3tm1Jfz
Rag2tm1Fwa/Rag2tm1Fwa
Tg(Cd4-cre)1Cwi/0
Tg(Tcra5CC7,Tcrb5CC7)IWep/0
Genetic
Background
involves: 129S/SvEv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata3tm1Jfz mutation (0 available); any Gata3 mutation (32 available)
Rag2tm1Fwa mutation (45 available); any Rag2 mutation (119 available)
Tg(Cd4-cre)1Cwi mutation (10 available)
Tg(Tcra5CC7,Tcrb5CC7)IWep mutation (5 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• T cells expressing the transgenic MHC class II-restricted TCR show diversion from the CD4+ lineage to the CD8+ lineage

hematopoietic system
• T cells expressing the transgenic MHC class II-restricted TCR show diversion from the CD4+ lineage to the CD8+ lineage


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory