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Phenotypes Associated with This Genotype
Genotype
MGI:3822771
cn8
Allelic
Composition
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Hesx1tm1(cre)Jpmb/Hesx1tm1Icar
Genetic
Background
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1Sor mutation (7 available); any Gt(ROSA)26Sor mutation (1026 available)
Hesx1tm1(cre)Jpmb mutation (0 available); any Hesx1 mutation (14 available)
Hesx1tm1Icar mutation (0 available); any Hesx1 mutation (14 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• telencepepahlic vesicle development is often asymmetric in embryos, with the right side being more severely affected
• very small telencephalic vesicle is sometimes observed at the 8-10 somite stage

vision/eye
• development of optic vesicles is often asymmetric with right side more severely affected


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory