Analysis Tools
nervous system
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• 26% of embryos analyzed show reduced telencephalic tissue at 12.5-14.5 dpc (days post coitum)
• severity and frequency of forebrain defects are increased in double heterozygotes, due to Hesx1 dosage decrease
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vision/eye
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• all embryos analyzed display severe bilateral microphthalmia or anophthalmia between 12.5 and 14.5 dpc
• some affected embryos also show reduction in telencephalic tissue
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anophthalmia
(
J:142649
)
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• all embryos analyzed display severe bilateral microphthalmia or anophthalmia between 12.5 and 14.5 dpc
• some affected embryos also show reduction in telencephalic tissue
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