Phenotypes Associated with This Genotype

Genotype
MGI:3833392

• Allelic Composition: Tg(Thy1-SERPINI1*G392E)333Icka/0
• Genetic Background: involves: C57BL * CD-1 * DBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased susceptibility to pharmacologically induced seizures ( J:144649 )

• kainate-treated mice exhibit decreased latency to seizure and increased seizure stage compared to similarly treated wild-type mice

nervous system

increased susceptibility to pharmacologically induced seizures ( J:144649 )

• kainate-treated mice exhibit decreased latency to seizure and increased seizure stage compared to similarly treated wild-type mice

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
familial encephalopathy with neuroserpin inclusion bodies		DOID:0050831	OMIM:604218	J:144649