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Phenotypes Associated with This Genotype
Genotype
MGI:3834683
Allelic
Composition
Tg(SFTPC-EML4/ALK)502-4Hima/0
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• mice develop lung adenocarcinoma a few weeks after birth
• however, treatment with an ALK inhibitor reduces tumor burden

respiratory system
• mice develop lung adenocarcinoma a few weeks after birth
• however, treatment with an ALK inhibitor reduces tumor burden

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
lung cancer DOID:1324 OMIM:211980
OMIM:608935
OMIM:612571
OMIM:612593
OMIM:614210
J:142679


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory