mortality/aging
• mice die from neurological disease with a mean lifespan of around 704 days
• the length of illness (mean day of onset until death) is around 293 days
|
behavior/neurological
• mice suffering form neurological disease tightly clasp hindlimbs upon lifting by tail
|
• mice develop ataxia with extension of hindlimbs and unbalanced posture with an age of onset around 452 days
|
• mice develop ataxia with extension of hindlimbs and unbalanced posture with an age of onset around 452 days
|
skeleton
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
Creutzfeldt-Jakob disease | DOID:11949 |
OMIM:123400 |
J:142098 |