Phenotypes for Creb1 Lrp5 Tg(Col1a1-cre)1Kry MGI:3837412 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Creb1^tm3Gsc/Creb1⁺ Lrp5^tm1Kry/Lrp5⁺ Tg(Col1a1-cre)1Kry/0
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Creb1^tm3Gsc mutation (2 available); any Creb1 mutation (61 available)
Lrp5^tm1Kry mutation (0 available); any Lrp5 mutation (82 available)
Tg(Col1a1-cre)1Kry mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

decreased bone mass ( J:146078 )

• phenotype is indistinguishable from mice homozygous null for Lrp5

decreased bone ossification ( J:146078 )

• decreased bone formation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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