Phenotypes for Ttr MGI:3838189 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ttr^tm2(TTR)Kymm/Ttr^{tm3(TTR*)Kymm}
Genetic Background	B6.Cg-Ttr^tm2(TTR)Kymm/Ttr^{tm3(TTR*)Kymm}

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ttr^tm2(TTR)Kymm mutation (0 available); any Ttr mutation (47 available)
Ttr^{tm3(TTR*)Kymm} mutation (0 available); any Ttr mutation (47 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

abnormal circulating protein level ( J:146510 )

• transthyretin tetramer complexes in the blood are extremely low despite normal expression of knocked-in genes in the liver

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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