Analysis Tools
digestive/alimentary system
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• rates of HCO3- influx during Cl- removal and HCO3- efflux during Cl- replacement in villi epithelia are decreased by 65% to 80% compared to in wild-type cells
• the sulfate ions/bicarbonate exchange is eliminated in duodenum epithelium
• baseline pH in villous epithelia is increased compared to in wild-type cells
• however, baseline pH is increased to wild-type levels in the absence of carbon dioxide/bicarbonate ions or during methazolamide treatment
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