Phenotypes for Cdkn2a Pdgfrb MGI:3842679 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cdkn2a^tm3(cre)Cjs/Cdkn2a^tm4Cjs Pdgfrb^tm11Sor/Pdgfrb^tm11Sor
Genetic Background	involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn2a^tm3(cre)Cjs mutation (0 available); any Cdkn2a mutation (67 available)
Cdkn2a^tm4Cjs mutation (2 available); any Cdkn2a mutation (67 available)
Pdgfrb^tm11Sor mutation (1 available); any Pdgfrb mutation (87 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

vision/eye phenotype ( J:147752 )

N	• at 3 months of age, all mutants have normal visual acuity • no retinal pathology is evident and vitreous is clear • normal vision is in contrast to Cdnk2a compound heterozygotes not carrying the floxed Pdgfr allele which show significantly compromised visual acuity

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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