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Phenotypes Associated with This Genotype
Genotype
MGI:3844657
Allelic
Composition		 Myf6tm1(cre)Mrc/Myf6+
Pax3tm1Mrc/Pax3tm1Mrc
Trp53tm1Brn/Trp53+
Genetic
Background		 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myf6tm1(cre)Mrc mutation (0 available); any Myf6 mutation (19 available)
Pax3tm1Mrc mutation (1 available); any Pax3 mutation (50 available)
Trp53tm1Brn mutation (18 available); any Trp53 mutation (240 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased rhabdomyosarcoma incidence ( J:93444 )
• 1 in 12 mice develop an rhabdomyosarcoma by day 202

muscle
increased rhabdomyosarcoma incidence ( J:93444 )
• 1 in 12 mice develop an rhabdomyosarcoma by day 202

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
alveolar rhabdomyosarcoma DOID:4051 OMIM:268220
 J:93444

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory