Phenotypes Associated with This Genotype

Genotype
MGI:3849881

• Allelic Composition: Thrb^tm6.1Few/Thrb^tm6.1Few
• Genetic Background: involves: 129 * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:150008 )

N • thyroid-stimulating hormone serum levels are normal

increased circulating thyroxine level ( J:150008 )

• 3 to 4 times higher than in wild-type mice

increased circulating triiodothyronine level ( J:150008 )

• 3 to 4 times higher than in wild-type mice

growth/size/body

decreased body weight ( J:150008 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
thyroid hormone resistance syndrome		DOID:11633	OMIM:188570 OMIM:274300	J:150008