Phenotypes for Mc3r Mc4r MGI:3850836 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mc3r^tm1Lvp/Mc3r^tm1Lvp Mc4r^tm1Dhu/Mc4r^tm1Dhu
Genetic Background	involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mc3r^tm1Lvp mutation (0 available); any Mc3r mutation (31 available)
Mc4r^tm1Dhu mutation (0 available); any Mc4r mutation (48 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

increased body weight ( J:64365 )

• at 26 weeks, female mice are 27% heavier than Mc4r^tm1Dhu homozygotes

• at 26 weeks, male mice are 13% heavier than Mc4r^tm1Dhu homozygotes

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
obesity		DOID:9970	OMIM:601665	J:64365

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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