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Phenotypes Associated with This Genotype
Genotype
MGI:4352677
cx2
Allelic
Composition		 Nfkb2tm2Brv/Nfkb2tm2Brv
Traf3tm1Bal/Traf3tm1Bal
Genetic
Background		 involves: 129S1/Sv * 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nfkb2tm2Brv mutation (1 available); any Nfkb2 mutation (50 available)
Traf3tm1Bal mutation (0 available); any Traf3 mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:124635 )
N
• unlike Traf3tm1Bal homozygotes, mice survive into adulthood

immune system
immune system phenotype ( J:124635 )
N
• mice do not exhibit the immune defects observed in single homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory