Phenotypes Associated with This Genotype

Genotype
MGI:4355902

• Allelic Composition: Tg(GFAP-tTA)67Pop/0; Tg(tetO-Ifng)184Pop/0
• Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased medulloblastoma incidence ( J:94092 )

• when doxycycline treatment is stopped at E 16, around 90% of double mutants develop medulloblastoma and die by P21

nervous system

increased medulloblastoma incidence ( J:94092 )

• when doxycycline treatment is stopped at E 16, around 90% of double mutants develop medulloblastoma and die by P21

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
medulloblastoma		DOID:0050902	OMIM:155255	J:94092