Phenotypes for Hoxa5 Hoxa6 Hoxb5 Hoxb6 Hoxc5 Hoxc6 MGI:4358354 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Hoxa5^tm1Rob/Hoxa5⁺ Hoxa6^tm1Mrc/Hoxa6⁺ Hoxb5^tm1Mrc/Hoxb5⁺ Hoxb6^tm1Mrc/Hoxb6⁺ Hoxc5^tm1Mrc/Hoxc5⁺ Hoxc6^tm1Dds/Hoxc6⁺
Genetic Background	involves: 129S/SvEv * 129S7/SvEvBrd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa5^tm1Rob mutation (1 available); any Hoxa5 mutation (28 available)
Hoxa6^tm1Mrc mutation (0 available); any Hoxa6 mutation (9 available)
Hoxb5^tm1Mrc mutation (0 available); any Hoxb5 mutation (11 available)
Hoxb6^tm1Mrc mutation (0 available); any Hoxb6 mutation (14 available)
Hoxc5^tm1Mrc mutation (0 available); any Hoxc5 mutation (12 available)
Hoxc6^tm1Dds mutation (0 available); any Hoxc6 mutation (11 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal skeleton morphology ( J:124112 )

• primaxial and abaxial skeleton defects are less severe than in either triple homozygote

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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