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Phenotypes Associated with This Genotype
Genotype
MGI:4358583
hm2
Allelic
Composition		 Thratm2Jas/Thratm2Jas
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Thratm2Jas mutation (1 available); any Thra mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating thyroxine level ( J:126521 )
• mice exhibit decreased thyroxine levels compared with wild-type mice
• after a low-iodine diet and propylthiouracil, TSH serum levels increase to 50% of wild-type

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory