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Phenotypes Associated with This Genotype
Genotype
MGI:4366767
cn4
Allelic
Composition		 Ets2tm1Rgo/Ets2tm5.1Rgo
Tg(MMTV-PyVT)634Mul/0
Tg(S100a4-cre)1Gle/0
Genetic
Background		 involves: 129S2/SvPas * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ets2tm1Rgo mutation (1 available); any Ets2 mutation (39 available)
Ets2tm5.1Rgo mutation (0 available); any Ets2 mutation (39 available)
Tg(MMTV-PyVT)634Mul mutation (2 available)
Tg(S100a4-cre)1Gle mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased mammary gland tumor incidence ( J:153747 )
• fewer mammary tumors form than in Ets2tm1Rgo/Ets2tm5.1Rgo Tg(MMTV-PyVT)634Mul mice and progression to adenoma and early carcinoma is slowed

integument
decreased mammary gland tumor incidence ( J:153747 )
• fewer mammary tumors form than in Ets2tm1Rgo/Ets2tm5.1Rgo Tg(MMTV-PyVT)634Mul mice and progression to adenoma and early carcinoma is slowed

endocrine/exocrine glands
decreased mammary gland tumor incidence ( J:153747 )
• fewer mammary tumors form than in Ets2tm1Rgo/Ets2tm5.1Rgo Tg(MMTV-PyVT)634Mul mice and progression to adenoma and early carcinoma is slowed

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory