Phenotypes Associated with This Genotype

Genotype
MGI:4397672

• Allelic Composition: Kcnq2^tm1.1Naas/Kcnq2^tm1.1Naas
• Genetic Background: FVB.129-Kcnq2^tm1.1Naas

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:154582 )

• most mice die between P16 and P30

postnatal lethality, incomplete penetrance ( J:154582 )

• most mice die between P16 and P30

prenatal lethality, incomplete penetrance ( J:154582 )

• fewer than expected mice were born

nervous system

seizures ( J:154582 )

• mice exhibit rapid onset of spontaneous seizures that result in death

growth/size/body

decreased body size ( J:154582 )

behavior/neurological

seizures ( J:154582 )

• mice exhibit rapid onset of spontaneous seizures that result in death

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
benign neonatal seizures		DOID:14264	OMIM:121200 OMIM:121201 OMIM:269720	J:154582