mortality/aging
• most mice die by 1 month of age
|
nervous system
• in the brain stem and spinal cord at P21
|
skeleton
• in mice that survive beyond 1 month
|
behavior/neurological
• in mice that survive beyond 1 month
|
paraparesis
(
J:154248
)
• mice that survive beyond 1 month exhibit hind limb weakness
|
growth/size/body
• at 3 weeks of age
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
Werdnig-Hoffmann disease | DOID:13137 |
OMIM:253300 |
J:154248 |