Phenotypes for Tbx1 Tfap2a MGI:4410369 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Tbx1^tm2.1Bem/Tbx1⁺ Tfap2a^tm1(cre)Moon/Tfap2a⁺
Genetic Background	either: (involves: 129/Sv * C57BL/6 * C57BL/6J * SJL) or (involves: 129/Sv * C57BL/6J * CBA * SJL)

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tbx1^tm2.1Bem mutation (0 available); any Tbx1 mutation (36 available)
Tfap2a^tm1(cre)Moon mutation (1 available); any Tfap2a mutation (39 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Fourth pharyngeal arch artery aplasia in Tbx1^tm2.1Bem/Tbx1⁺ Tfap2a^tm1(cre)Moon/Tfap2a⁺ mice

cardiovascular system

fourth pharyngeal arch artery hypoplasia ( J:154590 )

• at E10.5, 76% of mice exhibit hypoplasia of the fourth pharyngeal aortic arch

craniofacial

fourth pharyngeal arch artery hypoplasia ( J:154590 )

• at E10.5, 76% of mice exhibit hypoplasia of the fourth pharyngeal aortic arch

embryo

fourth pharyngeal arch artery hypoplasia ( J:154590 )

• at E10.5, 76% of mice exhibit hypoplasia of the fourth pharyngeal aortic arch

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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