Phenotypes Associated with This Genotype

Genotype
MGI:4415304

cx6

• Allelic Composition: Etv4^tm1Arbr/Etv4^tm1Arbr; Etv5^tm1Hass/Etv5⁺
• Genetic Background: involves: 129S1/Sv

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

abnormal kidney morphology ( J:155594 )

• hypoplastic kidneys are small and cystic, lack nephrogenic zone and have greatly reduced tubular elements and glomeruli compared to in wild-type mice

kidney cyst ( J:155594 )

renal hypoplasia ( J:155594 )

• in 52% of mice

abnormal nephron morphology ( J:155594 )

• kidneys lack the nephorgenic zone

decreased renal glomerulus number ( J:155594 )

decreased renal tubule number ( J:155594 )

absent kidney ( J:155594 )

• in 41% of mice

absent ureter ( J:155594 )

• in 22% of mice

growth/size/body

kidney cyst ( J:155594 )