homeostasis/metabolism
• in fed mice and mice fed a high fat diet
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• in fasting mice and mice fed a high fat diet
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• in mice fed regular chow or a high fat diet
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• glucose clearance is modestly increased compared to in wild-type mice
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• indicated by reduced fasting plasma insulin and free fatty acid
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behavior/neurological
• in mice fed a high fat diet
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• in mice fed regular chow or a high fat diet
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adipose tissue
• in mice fed regular chow or a high fat diet
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growth/size/body
• in mice fed regular chow or a high fat diet
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