About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4418448
Allelic
Composition		 Cdkn2atm1Rdp/Cdkn2atm1Rdp
Ptentm1Rps/Ptentm1Rps
Tg(Tyr-cre/ERT2)13Bos/0
Genetic
Background		 involves: 129/Sv * 129S1/Sv * C57BL/6J * FVB/N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn2atm1Rdp mutation (6 available); any Cdkn2a mutation (67 available)
Ptentm1Rps mutation (1 available); any Pten mutation (88 available)
Tg(Tyr-cre/ERT2)13Bos mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased melanoma incidence ( J:155731 )
• following 4-hydroxytamoxifen (4-OHT) application, all mice develop melanoma over a 9 month period unlike wild-type mice

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
melanoma DOID:1909 J:155731

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory