behavior/neurological
nervous system
growth/size/body
• average kidney weights of 3 week olds are elevated to 2.6% of body weight compared to the wild-type value of 0.7%
|
• average liver weights of 3 week old mice are elevated to 15.6% of body weight compared to the wild-type value of 4.6%
|
homeostasis/metabolism
• plasma lactic acid levels are elevated 1.6 fold
|
• elevated 1.6 fold
|
hypoglycemia
(
J:155990
)
• 7.2 fold higher than that in the control littermates
|
• 15.9 fold higher than that in the control littermates
|
• glycogen accumulation in the tubular epithelial cells of the kidney
|
• glycogen accumulation in the hepatocytes of the liver
|
renal/urinary system
• average kidney weights of 3 week olds are elevated to 2.6% of body weight compared to the wild-type value of 0.7%
|
• glycogen accumulation in the tubular epithelial cells of the kidney
|
liver/biliary system
• average liver weights of 3 week old mice are elevated to 15.6% of body weight compared to the wild-type value of 4.6%
|
• glycogen accumulation in the hepatocytes of the liver
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
glycogen storage disease Ia | DOID:2749 |
OMIM:232200 |
J:155990 |