Phenotypes Associated with This Genotype

Genotype
MGI:4421547

hm1

• Allelic Composition: Ednrb^s/Ednrb^s
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

white spotting ( J:12952 )

• Background Sensitivity: size of spots is variable depending on modifiers

variable body spotting ( J:12952 , J:30758 )

• Background Sensitivity: location and size of spots are variable depending on modifiers (J:12952)

• Background Sensitivity: this genotype may result in an entirely or almost entirely unpigmented phenotype or a mouse with few white spots of variable size (J:12952)

• Background Sensitivity: background modifiers determine extent (J:30758)

• predictable locations for spotting include the feet, tail, head, tip of nose, umbilical area, lumbar region and shoulders (J:30758)

abnormal foot pigmentation ( J:30758 )

abnormal tail pigmentation ( J:30758 )

variable depigmentation ( J:30758 )

limbs/digits/tail

abnormal tail pigmentation ( J:30758 )

digestive/alimentary system

megacolon ( J:15014 )

• Background Sensitivity: as many as 10% of any litter of homozygotes may exhibit megacolon

integument

white spotting ( J:12952 )

• Background Sensitivity: size of spots is variable depending on modifiers

variable body spotting ( J:12952 , J:30758 )

• Background Sensitivity: location and size of spots are variable depending on modifiers (J:12952)

• Background Sensitivity: this genotype may result in an entirely or almost entirely unpigmented phenotype or a mouse with few white spots of variable size (J:12952)

• Background Sensitivity: background modifiers determine extent (J:30758)

• predictable locations for spotting include the feet, tail, head, tip of nose, umbilical area, lumbar region and shoulders (J:30758)

abnormal foot pigmentation ( J:30758 )

abnormal tail pigmentation ( J:30758 )

variable depigmentation ( J:30758 )