Phenotypes for Cd74 Lmo2 Smim3 Trp53 MGI:4421780 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Smim3^tm1Anjm/Smim3⁺ Cd74^tm1Anjm/Cd74⁺ Lmo2^tm2(cre)Thr/Lmo2⁺ Trp53^tm1Brd/Trp53^tm1Brd
Genetic Background	involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd74^tm1Anjm mutation (0 available); any Cd74 mutation (36 available)
Lmo2^tm2(cre)Thr mutation (0 available); any Lmo2 mutation (31 available)
Smim3^tm1Anjm mutation (0 available); any Smim3 mutation (9 available)
Trp53^tm1Brd mutation (5 available); any Trp53 mutation (239 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:155870 )

N	• absence of Trp53 expression completely rescues hematopoetic defects seen in mutant mice wild-type for Trp53

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
chromosome 5q deletion syndrome		DOID:0090016	OMIM:153550	J:155870

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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