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Phenotypes Associated with This Genotype
Genotype
MGI:4436771
cn4
Allelic
Composition
Ntf3tm1Esm/Ntf3tm1Esm
Tg(GFAP-cre)25Mes/0
Genetic
Background
involves: 129S1/Sv * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ntf3tm1Esm mutation (0 available); any Ntf3 mutation (24 available)
Tg(GFAP-cre)25Mes mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• loss of subcortical tract results in a reduction in axonal bundles in subcortical white matter

vision/eye
• impaired visual function indicated by the visual cliff avoidance test: mutants often cross the cliff edge without hesitation and show no preference for either side of the box


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory