Phenotypes Associated with This Genotype

Genotype
MGI:4440922

• Allelic Composition: Tg(Eno2-MFN2*R94Q)L51Ugfm/0
• Genetic Background: involves: C57BL/6 * C57BL/6J * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal locomotor behavior ( J:158936 )

• mice exhibit locomotor impairments compared with wild-type mice

nervous system

abnormal axon morphology ( J:158936 )

• mice exhibit a shift in the size of myelinated axons compared with wild-type mice

• axons contain more mitochondria than wild-type axons

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Charcot-Marie-Tooth disease type 2A2A		DOID:0110155	OMIM:609260	J:158936