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Phenotypes Associated with This Genotype
Genotype
MGI:4441397
cn7
Allelic
Composition		 Nr2f2tm2.1Tsa/Nr2f2tm2.1Tsa
Rbpjtm1Hon/Rbpjtm1Hon
Tg(Tek-cre)1Ywa/0
Genetic
Background		 involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr2f2tm2.1Tsa mutation (0 available); any Nr2f2 mutation (28 available)
Rbpjtm1Hon mutation (2 available); any Rbpj mutation (193 available)
Tg(Tek-cre)1Ywa mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, incomplete penetrance ( J:158959 )
• fewer embryos than expected are found at E10.0

immune system
decreased lymphatic vessel endothelial cell number ( J:158959 )
• at E10.0, number of Prox1+ve lymphatic endothelial cells is dramatically reduced

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory